BAY 1816032

Name: BAY 1816032
Brand: Tocris Bioscience
SKU: 7549

Tocris Bioscience, part of Bio-Techne | Catalog # 7549

Citations (2)

COA / SDS

Potent and selective BUB1 kinase inhibitor

Key Product Details

Chemical Name:	2-[3,5-Difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1H-indazol-1-yl]methyl]phenoxy]ethanol
Purity:	≥98%

View Full Technical Details for BAY 1816032

Technical Data
Citations

Biological Activity for BAY 1816032

BAY 1816032 is a potent and selective inhibitor of BUB1 kinase, a mitotic checkpoint serine/threonine kinase (IC₅₀ = 6.1 nM). BAY 1816032 shows 17-fold selectivity over a panel of 403 other human kinases. In vivo, BAY 1816032 decreases tumor size in tumor xenograft models. BAY 181603 is orally bioavailable.

Technical Data for BAY 1816032

Formula	C₂₇H₂₄F₂N₆O₄
Storage	Store at -20°C
Purity	≥98%
CAS Number	1891087-61-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for BAY 1816032

Solubility

Soluble Soluble to 50 mM in DMSO

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Product Documents for BAY 1816032

COA

Certificate of Analysis

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