Checkpoint Control Kinase Inhibitors: Small Molecules and Peptides
16 results for "Checkpoint Control Kinase Inhibitors Small Molecules and Peptides" in Products
16 results for "Checkpoint Control Kinase Inhibitors Small Molecules and Peptides" in Products
Checkpoint Control Kinase Inhibitors: Small Molecules and Peptides
Potent and selective ATM kinase inhibitor
| Chemical Name: | 2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one |
| Purity: | ≥98% |
Potent and selective BUB1 kinase inhibitor
| Chemical Name: | 2-[3,5-Difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1H-indazol-1-yl]methyl]phenoxy]ethanol |
| Purity: | ≥98% |
Inhibitor of PI 3-kinase, mTOR and DNA-PK
| Chemical Name: | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Purity: | ≥98% |
Selective Mps1 kinase inhibitor
| Chemical Name: | 1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol dihydrochloride |
| Purity: | ≥98% |
Potent and selective Mps1 kinase inhibitor
| Chemical Name: | 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one |
| Purity: | ≥99% (HPLC) |
Potent and selective DNA-PK inhibitor
| Chemical Name: | 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one |
| Purity: | ≥99% |
Potent and selective inhibitor of Chk1 and Wee1
| Chemical Name: | 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |
| Purity: | ≥98% (HPLC) |
Chk1 inhibitor
| Chemical Name: | 9,10,11,12-Tetrahydro- 9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione |
| Purity: | ≥98% |
Potent and selective Wee1 inhibitor
| Chemical Name: | 1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one |
| Purity: | ≥98% |
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
| Chemical Name: | 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride |
| Purity: | ≥99% (HPLC) |
Selective Chk2 inhibitor
| Chemical Name: | 2,2'-[Carbonylbis(imino-4,1-phenyleneethylidyne]bishydrazinecarboximidamide) bis(4-methylbenzenesulfonate) |
| Purity: | ≥98% |
Selective DNA-PK inhibitor
| Chemical Name: | 2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one |
| Purity: | ≥98% (HPLC) |
MRN-ATM pathway inhibitor
| Chemical Name: | Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one |
| Purity: | ≥99% (HPLC) |
Dual DNA-PK and PI 3-K inhibitor
| Chemical Name: | 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide |
| Purity: | ≥97% |
Cdk inhibitor; potently inhibits cdk9; also inhibits MK2
| Chemical Name: | 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride |
| Purity: | ≥99% (HPLC) |
Selective Chk1 inhibitor
| Chemical Name: | (R)-α-Amino-N-[5,6-dihydro-2-(1-methyl-1H-pyrazol-4-yl)-6-oxo-1H-pyrrolo[4,3,2-ef][2,3]benzodiazepin-8-yl]-cyclohexaneacetamide |
| Purity: | ≥99% |
