Ceefourin 1

Name: Ceefourin 1
Brand: Tocris Bioscience
SKU: 5867

Tocris Bioscience, part of Bio-Techne | Catalog # 5867

Citations (4)

COA / SDS

Selective MRP4 inhibitor

Key Product Details

Chemical Name:	5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione
Purity:	≥98%

View Full Technical Details for Ceefourin 1

Technical Data
Citations

Biological Activity for Ceefourin 1

Ceefourin 1 is a selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC₅₀ = 2.6 μM). Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 (Cat. No. 2684). Ceefourin 1 inhibits cAMP efflux from acute myeloid leukemia cells (AML) and promotes apoptosis in combination with Histamine (Cat. No. 3545).

Technical Data for Ceefourin 1

Formula	C₁₁H₁₀N₄S₃
Storage	Store at +4°C
Purity	≥98%
CAS Number	315702-40-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ceefourin 1

Solubility

Soluble Soluble to 100 mM in DMSO

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Ceefourin 1

References are publications that support the biological activity of the product.

Cheung et al. High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem.Pharmacol., 2014;91:97 PMID: 24973542

Ceefourin 1

Tocris Bioscience, part of Bio-Techne | Catalog # 5867

Key Product Details

Biological Activity for Ceefourin 1

Technical Data for Ceefourin 1

Solubility for Ceefourin 1

Dilution Calculator

Reconstitution Calculator

References for Ceefourin 1

Product Documents for Ceefourin 1

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected