CGS 19755

Name: CGS 19755
Brand: Tocris Bioscience
SKU: 1241

Tocris Bioscience, part of Bio-Techne | Catalog # 1241

Citations (20)

COA / SDS

Potent competitive NMDA antagonist

Key Product Details

Description:	Potent competitive NMDA antagonist
Chemical Name:	cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid
Molecular Weight:	223.17

View Full Technical Details for CGS 19755

Technical Data
Citations

Biological Activity for CGS 19755

CGS 19755 is a potent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective.

Technical Data for CGS 19755

M. Wt	223.17
Formula	C₇H₁₄NO₅P
Storage	Store at RT
CAS Number	110347-85-8
PubChem ID	6604838
InChi Key	LPMRCCNDNGONCD-NTSWFWBYSA-N
Smiles	O=P(C[C@@H]1C[C@H]([C@](O)=O)NCC1)(O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CGS 19755

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	5.58	25

Preparing Stock Solutions for CGS 19755

The following data is based on the product molecular weight 223.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	17.92 mL	89.62 mL	179.24 mL
1.25 mM	3.58 mL	17.92 mL	35.85 mL
2.5 mM	1.79 mL	8.96 mL	17.92 mL
12.5 mM	0.36 mL	1.79 mL	3.58 mL

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References for CGS 19755

References are publications that support the biological activity of the product.

Lehmann CGS 19755, a selective and competitive N-MthD.-aspartate-type excitatory amino acid receptor antagonist. J.Pharmacol.Exp.Ther. 1988 PMID: 2899170
Perez-Pinzon Correlation of CGS 19755 neuroprotection against in vivo excitotoxicity and focal cerebral ischemia. J.Cereb.Blood Flow Metab. 1995 PMID: 7673380
Bennett Behavioral pharmacological profile of CGS 19755, a competitive antagonist at N-MthD.-aspartate receptors. J.Pharmacol.Exp.Ther. 1989 PMID: 2547931