NMDA Receptor Antagonists: Small Molecules and Peptides
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity.
39 results for "NMDA Receptor Antagonists Small Molecules and Peptides" in Products
39 results for "NMDA Receptor Antagonists Small Molecules and Peptides" in Products
NMDA Receptor Antagonists: Small Molecules and Peptides
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family and function in synaptic plasticity, neuronal development and excitotoxicity.
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
| Alternate Names: | 2-APV,D-APV,D-2-amino-5-phosphonovalerate |
| Chemical Name: | D-(-)-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥99% (HPLC) |
Non-competitive NMDA receptor antagonist
| Chemical Name: | 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
| Purity: | ≥99% (HPLC) |
NMDA receptor antagonist; enantiomer of ketamine hydrochloride (Cat. No. 3131); neuroprotective
| Chemical Name: | (S)-(+)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective NMDA antagonist
| Alternate Names: | DL-APV |
| Chemical Name: | DL-2-Amino-5-phosphonopentanoic acid |
| Purity: | ≥98% (HPLC) |
Potent NMDA antagonist; more active enantiomer of (RS)-CPP
| Chemical Name: | 3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid |
Potent and selective NMDA antagonist; sodium salt of DL-AP5
| Chemical Name: | DL-2-Amino-5-phosphonopentanoic acid sodium salt |
| Purity: | ≥98% (HPLC) |
Non-competitive NMDA antagonist; acts at ion channel site
| Alternate Names: | Dizocilpine |
| Chemical Name: | (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate |
| Purity: | ≥99% (HPLC) |
Potent and selective non-NMDA iGluR antagonist
| Alternate Names: | Cyanquixaline |
| Chemical Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione |
| Purity: | ≥99% (HPLC) |
GluN2B-selective NMDA antagonist
| Chemical Name: | (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate |
| Purity: | ≥98% (HPLC) |
NMDA antagonist; antidepressant; may not display psychotomimetic or addictive side effects of (S)-ketamine
| Chemical Name: | (R)-(-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent kynurenine 3-monooxygenase (KMO) inhibitor
| Chemical Name: | 3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide |
| Purity: | ≥99% (HPLC) |
NMDA antagonist; acts at ion channel site
| Chemical Name: | 3,5-Dimethyl-tricyclo[3.3.1.13,7]decan-1-amine hydrochloride |
Non-competitive NMDA antagonist; also σ ligand
| Chemical Name: | (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate |
| Purity: | ≥99% (HPLC) |
NMDA antagonist; less active enantiomer of (+)-MK 801
| Chemical Name: | (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-imine maleate |
| Purity: | ≥99% (HPLC) |
Potent non-competitive NMDA antagonist; antinociceptive
| Chemical Name: | 2-Amino-2-(2-chlorophenyl)cyclohexanone hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent NMDA antagonist; acts at glycine site
| Chemical Name: | 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% (HPLC) |
Potent NMDA antagonist
| Chemical Name: | (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid |
GluN1/GluN2A-selective NMDA antagonist
| Chemical Name: | 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide |
| Purity: | ≥99% (HPLC) |
Non-competitive NMDA antagonist
| Alternate Names: | PCP |
| Chemical Name: | 1-(1-Phenylcyclohexyl)piperidine hydrochloride |
| Purity: | ≥99% (HPLC) |
Highly potent NMDA antagonist
| Chemical Name: | trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline |
| Purity: | ≥99% (HPLC) |
Potent and selective NMDA antagonist; acts at glycine site
| Alternate Names: | PAMQX |
| Chemical Name: | [(1S)-1-[[(7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]phosphonic acid hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist; acts at the glycine site
| Alternate Names: | GV 150526A |
| Chemical Name: | 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt |
| Purity: | ≥98% (HPLC) |
Potent and selective NMDA antagonist
| Chemical Name: | (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid |
| Purity: | ≥99% (HPLC) |
GluN2C/GluN2D-selective NMDA antagonist
| Chemical Name: | 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid |
| Purity: | ≥97% (HPLC) |
Non-competitive and GluN2C/GluN2D-selective NMDA antagonist
| Chemical Name: | 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)quinazolinyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
