Escitalopram oxalate

Name: Escitalopram oxalate
Brand: Tocris Bioscience
SKU: 4796

Tocris Bioscience, part of Bio-Techne | Catalog # 4796

Citations (6)

COA / SDS

Selective serotonin reuptake inhibitor (SSRI)

Key Product Details

Description:	Selective serotonin reuptake inhibitor (SSRI)
Chemical Name:	(+)-(S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
Purity:	≥98% (HPLC)
Molecular Weight:	414.43

View Full Technical Details for Escitalopram oxalate

Technical Data
Citations

Biological Activity for Escitalopram oxalate

Escitalopram oxalate is a selective 5-HT reuptake inhibitor (K_i values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Escitalopram oxalate is an S-enantiomer and eutomer of citalopram (Cat. No. 1427).

Compound Libraries for Escitalopram oxalate

Escitalopram oxalate is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Escitalopram oxalate

M. Wt	414.43
Formula	C₂₀H₂₁FN₂O.C₂H₂O₄
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	219861-08-2
PubChem ID	146571
InChi Key	KTGRHKOEFSJQNS-BDQAORGHSA-N
Smiles	FC(C=C3)=CC=C3[C@]1(CCCN(C)C)OCC2=C1C=CC(C#N)=C2.OC(C(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Escitalopram oxalate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	20.72	50
	DMSO	41.44	100

Preparing Stock Solutions for Escitalopram oxalate

The following data is based on the product molecular weight 414.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.41 mL	12.06 mL	24.13 mL
5 mM	0.48 mL	2.41 mL	4.83 mL
10 mM	0.24 mL	1.21 mL	2.41 mL
50 mM	0.05 mL	0.24 mL	0.48 mL

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References for Escitalopram oxalate

References are publications that support the biological activity of the product.

Zhang Structure-activity relationships for a novel series of cital. (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) analogues at monoamine transporters. J.Med.Chem. 2010 PMID: 20672825