OAC-1

Name: OAC-1
Brand: Tocris Bioscience
SKU: 4887

Tocris Bioscience, part of Bio-Techne | Catalog # 4887

COA / SDS

Oct4 activator; enhances iPSC reprogramming efficiency

Discontinued Product

4887 has been discontinued. View all Additional Stem Cell Dedifferentiation Products products.

Key Product Details

Description:	Oct4 activator; enhances iPSC reprogramming efficiency
Chemical Name:	N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
Purity:	≥98% (HPLC)
Molecular Weight:	237.26

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Technical Data
Citations

Biological Activity for OAC-1

OAC-1 is a Oct4 activator. Enhances and accelerates iPSC reprogramming in the presence of 4F (Oct4, Sox2, c-Myc and Klf4) by ~20-fold compared to 4F alone. Induces mRNA expression of Oct4, Sox2 and Nanog and also Tet1. Displays no effects on p53-p21 pathway or Wnt-β-catenin signaling.

Technical Data for OAC-1

M. Wt	237.26
Formula	C₁₄H₁₁N₃O
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	300586-90-7
PubChem ID	789882
InChi Key	HWJRIFZDXJKJJN-UHFFFAOYSA-N
Smiles	O=C(C3=CC=CC=C3)NC1=NC=C2C(C=CN2)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for OAC-1

References are publications that support the biological activity of the product.

Li Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proc.Natl.Acad.Sci.U S A 2012 PMID: 23213213

OAC-1

Tocris Bioscience, part of Bio-Techne | Catalog # 4887

Key Product Details

Biological Activity for OAC-1

Technical Data for OAC-1

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for OAC-1

Product Documents for OAC-1

COA

Certificate of Analysis

SDS

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