Additional Stem Cell Dedifferentiation Products: Small Molecules and Peptides
19 results for "Additional Stem Cell Dedifferentiation Products Small Molecules and Peptides" in Products
19 results for "Additional Stem Cell Dedifferentiation Products Small Molecules and Peptides" in Products
Additional Stem Cell Dedifferentiation Products: Small Molecules and Peptides
Highly selective GSK-3 inhibitor; acts as Wnt activator
| Alternate Names: | CHIR99021,CT99021 |
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥98% (HPLC) |
CHIR 99021 synthesized to cGMP guidelines
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥99% |
Potent and selective inhibitor of TGF-βRI
| Alternate Names: | E-616452,SJN 2511,ALK5 Inhibitor II |
| Chemical Name: | 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine |
| Purity: | ≥99% (HPLC) |
Potent inhibitor of MEK1/2
| Alternate Names: | PD325901 |
| Chemical Name: | N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| Purity: | ≥99% (HPLC) |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO
| Chemical Name: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Purity: | ≥97% (HPLC) |
p53 inhibitor. Also aryl hydrocarbon receptor agonist
| Chemical Name: | 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide |
GSK-3β inhibitor; also inhibits cdks
| Chemical Name: | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one |
| Purity: | ≥98% (HPLC) |
Potent histone deacetylase inhibitor
| Chemical Name: | (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
| Purity: | ≥95% (HPLC) |
DNA methyltransferase inhibitor
| Chemical Name: | 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one |
| Purity: | ≥98% (HPLC) |
RepSox synthesized to Ancillary Material Grade
| Alternate Names: | ALK5 Inhibitor II,SJN 2511,E-616452 |
| Chemical Name: | 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine |
| Purity: | ≥99% |
Retinoic acid analog; RAR agonist
| Alternate Names: | Ro 13-7410 |
| Chemical Name: | 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Irreversible inhibitor of LSD1; also inhibits MAO
| Alternate Names: | 2-PCPA |
| Chemical Name: | (±)-trans-2-Phenylcyclopropylamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Highly potent and selective GSK-3 inhibitor
| Chemical Name: | N6-[2-[[4-(2,4-Dichlorophenyl)-5-(1H-imidazol-1-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-2,6-pyridinediamine |
| Purity: | ≥98% (HPLC) |
Oct3/4 inducer; induces expression of pluripotent-associated genes
| Chemical Name: | Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate |
| Purity: | ≥98% (HPLC) |
Inhibitor of p53-mitochondrial binding
| Alternate Names: | NSC 303580 |
| Chemical Name: | 2-Phenylethynesulfonamide |
| Purity: | ≥99% (HPLC) |
GLP and G9a inhibitor
| Chemical Name: | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
| Purity: | ≥98% (HPLC) |
Non-nucleoside DNA methyltransferase inhibitor
| Chemical Name: | N-Phthalyl-L-tryptophan |
| Purity: | ≥99% (HPLC) |
Potent PDGFRα and PDGFRβ inhibitor; also inhibits c-Abl, Lck, c-Src and Fyn kinases
| Chemical Name: | N-(3-Fluorophenyl)-1,4-dihydro-6,7-dimethoxyindeno[1,2-c]pyrazol-3-amine |
| Purity: | ≥98% (HPLC) |
