PP 2

Biological Activity for PP 2

Technical Data for PP 2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for PP 2

References for PP 2

References are publications that support the biological activity of the product.

• Carrim N, Walsh T, Consonni A, Torti M, Berndt M, Metharom P Role of focal adhesion tyrosine kinases in GPVI-dependent platelet activation and reactive oxygen species formation. PLoS ONE, 2014;9(11):e113679. 2014 PMID: 25415317
• Giegold O, Ogrissek N, Richter C, Schroder M, Herrero San Juan M, Pfeilschifter J, Radeke H CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation. J Immunol, 2013;190(7):3696-705. 2013 PMID: 23447686
• Zhang, XinTian, Meng, Jun, Wang, Zhao-Yi A switch role of Src in the biphasic EGF signaling of ER-negative breast cancer cells. PLoS ONE, 2012;7(8):e41613. 2012 PMID: 22927910
• Bayliss A, Evans P Characterisation of AmphiAmR11, an amphioxus (Branchiostoma floridae) D2-dopamine-like G protein-coupled receptor. PLoS ONE, 2013;8(11):e80833. 2013 PMID: 24265838
• Lee E, Sidoryk-Wegrzynowicz M, Wang N, Webb A, Son D, Lee K, Aschner M GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes. J Biol Chem, 2012;287(32):26817-28. 2012 PMID: 22645130
• F Pareja, AH Brandes, T Basili, P Selenica, FC Geyer, D Fan, A Da Cruz Pa, R Kumar, DN Brown, R Gularte-Mé, B Alemar, R Bi, RS Lim, I de Bruijn, S Fujisawa, R Gardner, E Feng, A Li, EM da Silva, JR Lozada, P Blecua, L Cohen-Goul, AA Jungbluth, EA Rakha, IO Ellis, MIA Edelweiss, J Palazzo, L Norton, T Hollmann, M Edelweiss, BP Rubin, B Weigelt, JS Reis-Filho Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors Nat Commun, 2018;9(1):3533. 2018 PMID: 30166553
• Mitrugno A, Williams D, Kerrigan S, Moran N A novel and essential role for FcgammaRIIa in cancer cell-induced platelet activation. Blood, 2013;123(2):249-60. 2013 PMID: 24258815
• Bain et al. The specificities of protein kinase inhibitors: an update. Biochem.J., 2003;371:199 PMID: 12534346
• Hanke et al. Discovery of a novel, potent, and src family-selective tyrosine kinase inhibitor. J.Biol.Chem., 1996;271:695 PMID: 8557675
• Lawrence and Niu Protein kinase inhibitors: the tyrosine-specific protein kinases. Pharmacol.Ther., 1998;77:81 PMID: 9578319
• Sanna et al. A role for Src kinase in spontaneous epileptiform activity in the CA3 region of the hippocampus. Proc.Natl.Acad.Sci.U.S.A., 2000;97:8653 PMID: 10890901