SAR 216471 hydrochloride

Name: SAR 216471 hydrochloride
Brand: Tocris Bioscience
SKU: 5650

Tocris Bioscience, part of Bio-Techne | Catalog # 5650

Citations (1)

COA / SDS

Potent P2Y12 antagonist; orally available

Discontinued Product

5650 has been discontinued. View all P2Y Receptor Antagonists products.

Key Product Details

Description:	Potent P2Y₁₂ antagonist; orally available
Chemical Name:	5-Chloro-N-[6-[5-methyl-4-(1-oxobutyl)-1H-pyrazol-1-yl]-3-pyridazinyl]-1-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-1H-indole-3-carboxamide hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	599.51

View Full Technical Details for SAR 216471 hydrochloride

Technical Data
Citations

Biological Activity for SAR 216471 hydrochloride

SAR 216471 hydrochloride is a potent P2Y₁₂ antagonist (IC₅₀ = 17 nM). Displays antiplatelet and antithrombotic activity in vivo. Orally available.

Technical Data for SAR 216471 hydrochloride

M. Wt	599.51
Formula	C₂₈H₃₁ClN₈O₃.HCl
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1279829-64-9
PubChem ID	70926954
InChi Key	UQLWHBMSQKUYAI-UHFFFAOYSA-N
Smiles	ClC1=CC=C2C(C(C(NC3=CC=C(N4C(C)=C(C(CCC)=O)C=N4)N=N3)=O)=CN2CC(N5CCN(C)CC5)=O)=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for SAR 216471 hydrochloride

References are publications that support the biological activity of the product.

Boldron N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist. J.Med.Chem. 2014 PMID: 25075638

SAR 216471 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 5650

Key Product Details

Biological Activity for SAR 216471 hydrochloride

Technical Data for SAR 216471 hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for SAR 216471 hydrochloride

Product Documents for SAR 216471 hydrochloride

COA

Certificate of Analysis

SDS

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