P2Y Receptor Antagonists: Small Molecules and Peptides
Part of the are G protein-coupled receptor (GPCR) family, P2Y purinergic receptors are activated by extracellular adenine and uridine nucleotides. They are found in most human tissues. They also have diverse physiological roles.
17 results for "P2Y Receptor Antagonists Small Molecules and Peptides" in Products
17 results for "P2Y Receptor Antagonists Small Molecules and Peptides" in Products
P2Y Receptor Antagonists: Small Molecules and Peptides
Part of the are G protein-coupled receptor (GPCR) family, P2Y purinergic receptors are activated by extracellular adenine and uridine nucleotides. They are found in most human tissues. They also have diverse physiological roles.
Highly potent and selective P2Y1 antagonist
| Chemical Name: | (1R*,2S*)-4-[2-Iodo-6-(methylamino)-9H-purin-9-yl]-2-(phosphonooxy)bicyclo[3.1.0]hexane-1-methanol dihydrogen phosphate ester tetraammonium salt |
| Purity: | ≥96% (HPLC) |
High affinity and selective P2Y14 antagonist
| Chemical Name: | 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity P2Y12 antagonist
| Chemical Name: | Ethyl 5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate |
| Purity: | ≥98% (HPLC) |
Highly potent P2Y12 antagonist
| Chemical Name: | 1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt |
| Purity: | ≥95% (HPLC) |
Selective and competitive P2Y2 antagonist
| Chemical Name: | 5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide |
| Purity: | ≥97% (HPLC) |
Selective P2Y6 antagonist
| Chemical Name: | N,N''-1,4-Butanediylbis[N'-(3-isothiocyanatophenyl)thiourea |
| Purity: | ≥95% (HPLC) |
Non-selective P2 antagonist
| Chemical Name: | Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid tetrasodium salt |
Selective P2Y1 antagonist
| Chemical Name: | 2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetrasodium salt |
| Purity: | ≥98% (HPLC) |
Selective P2Y11 and P2X1 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-fluoro-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥90% (HPLC) |
P2Y12 antagonist
| Chemical Name: | 5-Chloro-N-[[[4-[6-Fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide |
| Purity: | ≥97% (HPLC) |
Non-selective P2 antagonist
| Chemical Name: | 8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid hexasodium salt |
| Purity: | ≥98% (HPLC) |
Competitive P2Y13 antagonist
| Chemical Name: | 2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt |
| Purity: | ≥96% (HPLC) |
Irreversible P2Y12 antagonist; antiplatelet and orally active
| Alternate Names: | LY640315,CS 747,Effient |
| Chemical Name: | 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone |
| Purity: | ≥98% (HPLC) |
Highly potent P2Y12 antagonist
| Alternate Names: | Cangrelor tetrasodium salt |
| Chemical Name: | N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]adenosine-5'-O-(β,γ-dichloromethylene)triphosphate tetrasodium salt |
| Purity: | ≥98% (HPLC) |
P2Y1 allosteric antagonist
| Chemical Name: | N-[2-[2-(1,1-Dimethylethyl)phenoxy]-3-pyridinyl]-N'-[4-(trifluoromethoxy)phenyl]urea |
| Purity: | ≥98% (HPLC) |
Selective P2Y12 antagonist
| Alternate Names: | Plavix |
| Chemical Name: | (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogen sulfate |
| Purity: | ≥99% (HPLC) |
Selective P2Y12 antagonist
| Alternate Names: | Plavix |
| Chemical Name: | Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrochloride |
| Purity: | ≥99% (HPLC) |
