Streptozocin

Name: Streptozocin
Brand: Tocris Bioscience
SKU: 1621
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 1621

(1)

Citations (10)

COA / SDS

DNA alkylator; antitumor and induces diabetes

Key Product Details

Description:	DNA alkylator; antitumor and induces diabetes
Alternative Names:	Streptozotocin
Chemical Name:	2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose
Purity:	≥95% (HPLC)
Molecular Weight:	265.22

View Full Technical Details for Streptozocin

Technical Data
Citations / Reviews (1)

Biological Activity for Streptozocin

Streptozocin is an antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.

Technical Data for Streptozocin

M. Wt	265.22
Formula	C₈H₁₅N₃O₇
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	18883-66-4
PubChem ID	2733335
InChi Key	ZSJLQEPLLKMAKR-YDEIVXIUSA-N
Smiles	O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1NC(N(C)N=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Streptozocin

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	26.52	100
	DMSO	26.52	100

Preparing Stock Solutions for Streptozocin

The following data is based on the product molecular weight 265.22.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.77 mL	18.85 mL	37.70 mL
5 mM	0.75 mL	3.77 mL	7.54 mL
10 mM	0.38 mL	1.89 mL	3.77 mL
50 mM	0.08 mL	0.38 mL	0.75 mL

Molarity Calculator

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Reconstitution Calculator

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References for Streptozocin

References are publications that support the biological activity of the product.

Weis Steptozotocin: A review of its pharmacology, efficacy and toxicity. Cancer Treat. Rep. 1982 PMID: 6277485
Bennett and Pegg Alkylation of DNA in rat tissues following administration of streptozotocin. Cancer Res. 1981 PMID: 6454479

Product Documents for Streptozocin

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Streptozocin (streptozotocin), which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov