VH 032 amide-alkylC2-amine

Name: VH 032 amide-alkylC2-amine
Brand: Tocris Bioscience
SKU: 6852

Tocris Bioscience, part of Bio-Techne | Catalog # 6852

COA / SDS

VHL ligand with alkyl linker and terminal amine for onward chemistry

Key Product Details

Description:	VHL ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names:	(S,R,S)-AHPC-C2-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)
Molecular Weight:	574.56

View Full Technical Details for VH 032 amide-alkylC2-amine

Technical Data
Citations

Biological Activity for VH 032 amide-alkylC2-amine

VH 032 amide-alkylC2-amine is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus an alkylC2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was VH 032 - linker 7

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for VH 032 amide-alkylC2-amine

M. Wt	574.56
Formula	C₂₅H₃₅N₅O₄S.2HCl
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2341796-73-2
Smiles	CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCN)=O)=O)O)=O)SC=N1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Product Documents for VH 032 amide-alkylC2-amine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.