VH 032 amide-alkylC7-amine

Name: VH 032 amide-alkylC7-amine
Brand: Tocris Bioscience
SKU: 7074

Tocris Bioscience, part of Bio-Techne | Catalog # 7074

Citations (17)

COA / SDS

VHL ligand with alkyl linker and terminal amine for onward chemistry

Key Product Details

Description:	VHL ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names:	(S,R,S)-AHPC-C7-NH₂
Chemical Name:	(2S,4R)-1-((S)-2-(8-Aminooctanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
Purity:	≥95% (HPLC)

View Full Technical Details for VH 032 amide-alkylC7-amine

Technical Data
Citations

Biological Activity for VH 032 amide-alkylC7-amine

VH 032 amide-alkylC7-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC^® research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used. This product is sold as an xHCl salt. The stoichiometry of the salt and hydration levels vary from batch to batch. It is sold in gross weight with the batch specific Molecular Weight available on the Certificate of Analysis

Technical Data for VH 032 amide-alkylC7-amine

Formula	C₃₀H₄₅N₅O₄S.xHCl
Storage	Store at -20°C
Purity	≥95% (HPLC)
InChi Key	RMNLYSBBFGSMFL-QVRKWNSCSA-N
Smiles	CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCCCCCCN)=O)=O)O)=O)SC=N1.Cl.
M. Wt	571.78 (Free Base)

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for VH 032 amide-alkylC7-amine

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.