VH 032 amide-PEG1-acid

Name: VH 032 amide-PEG1-acid
Brand: Tocris Bioscience
SKU: 7104

Tocris Bioscience, part of Bio-Techne | Catalog # 7104

COA / SDS

VHL ligand with PEG linker and terminal acid for onward chemistry

Key Product Details

Description:	VHL ligand with PEG linker and terminal acid for onward chemistry
Alternative Names:	(S,R,S)-AHPC-PEG1-COOH
Chemical Name:	3-(3-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)propanoic acid
Purity:	≥95% (HPLC)
Molecular Weight:	574.69

View Full Technical Details for VH 032 amide-PEG1-acid

Technical Data
Citations

Biological Activity for VH 032 amide-PEG1-acid

VH 032 amide-PEG1-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC^® research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for VH 032 amide-PEG1-acid

M. Wt	574.69
Formula	C₂₈H₃₈N₄O₇S
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2172820-07-2
PubChem ID	134184040
InChi Key	HVPZHRHEHKZOOJ-TYBLODHISA-N
Smiles	CC1=C(C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(C)C)NC(CCOCCC(O)=O)=O)=O)O)=O)SC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for VH 032 amide-PEG1-acid

COA

Certificate of Analysis

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