VH 101 phenol-alkylC4-amine

Name: VH 101 phenol-alkylC4-amine
Brand: Tocris Bioscience
SKU: 7293

Tocris Bioscience, part of Bio-Techne | Catalog # 7293

COA / SDS

VHL ligand with alkyl linker and terminal amine for onward chemistry

Key Product Details

Description:	VHL ligand with alkyl linker and terminal amine for onward chemistry
Chemical Name:	(2S,4R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Purity:	≥95% (HPLC)
Molecular Weight:	676.67

View Full Technical Details for VH 101 phenol-alkylC4-amine

Technical Data
Citations

Biological Activity for VH 101 phenol-alkylC4-amine

VH 101 phenol-alkylC4-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC^® research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC^® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Licensing Information

Sold under licence from the University of Dundee.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data for VH 101 phenol-alkylC4-amine

M. Wt	676.67
Formula	C₃₀H₄₂FN₅O₅S.2HCl
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	2564467-03-2
InChi Key	UQHSXRZQPDIVIY-OTCWRJAQSA-N
Smiles	CC1=C(SC=N1)C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@@H](NC(C4(CC4)F)=O)C(C)(C)C)=O)=O)C(OCCCCN)=C2.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Product Documents for VH 101 phenol-alkylC4-amine

COA

Certificate of Analysis

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