Lung Cancer Research Products
Research into the causes of lung cancer has focused on the inactivation of tumor suppressor genes, activation of oncogenes, and/or stimulation of growth factors. Many tumor suppressor genes are involved in the development and progression of lung cancer. In addition, gene rearrangements (ROS1, RET) and gene fusions (EML4-ALK, CD74-NRG1) are important targets of therapy in a subset of lung cancer patients. Vascular endothelial growth factor (VEGF) has been extensively studied as a major driver of lung cancer tumor development and metastasis. VEGF is often overexpressed as lung cancers progress, strongly associated with increased microvessel density, and linked to decreased survival.
Bio-Techne offers a large selection of lung cancer-related antibodies, proteins and inhibitors for a wide-range of tumor suppressors, oncogenes, gene rearrangement targets, and/or growth factors.
Tumor Suppressor Research
p53 Antibody (PAb 240) (Calatog # NB200-103) expression in human prostate cancer tissue. p53 was detected in immersion fixed paraffin-embedded sections of human prostate cancer using anti-human mouse monoclonal antibody. Tissue was stained using the VisuCyte anti-mouse HRP polymer detection reagent (Catalog # VC001) with DAB chromogen (brown) and counterstained with hematoxylin (blue; Catalog # 5222).
Oncogenes Research
Human EGFR Antibody: Identification of EGFR in lysate of A431 human epithelial carcinoma cell line by Simple Western™ using Goat Anti-Human EGFR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF231).
VEGF Pathway Research
Find research products for the vascular endothelial growth factor (VEGF) pathway.
Human VEGF165 Antibody: VEGF detection in human liver cancer tissue by immunohistochemistry using Goat Anti-Human VEGF 165 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-293-NA)