An Animal-Free Full Defined Workflow for Human iPSC Research

Human induced pluripotent stem cells (iPSCs) play a crucial role in generating ex vivo models for studying development, disease mechanisms and for drug discovery, as well as demonstrating significant potential for regenerative medicine applications. However, many iPSC workflows rely on undefined culture surfaces and animal-containing reagents. These pose challenges that can hinder seamless transition to the clinic, particularly in terms of regulatory compliance.

To address these issues, we have developed animal-free and fully defined iPSC workflows, ensuring the reproducibility of results and easier compliance with cGMP standards.

Download this animal-free human iPSC workflow poster to explore:

• The identification and assessment of human vitronectin constructs for supporting iPSC attachment and proliferation
• The performance of the animal component-free ExCellerate™ iPSC Expansion Media in enabling iPSC proliferation, growth, and maintaining pluripotency
• Animal-free differentiation processes for iPSCs into neurons and dopaminergic progenitors
• How animal-free reagents can be combined to create a standardized fully defined, and reproducible process for iPSC research and clinical translation