GPCR Efficacy and Biased Agonism
by Patrick M. Sexton, Arthur Christopoulos and Denise Wootten. Monash University & Fudan University
Life Science PostersG Protein-coupled receptors (GPCRs) mediate signal transduction via different signaling pathways. Biased signaling occurs when a ligand preferentially activates one signaling pathway over another with the potential for different physiological outcome. Written by Patrick M. Sexton, Arthur Christopoulos, and Denise Wootten, the GPCR Efficacy and Biased Agonism Life Science Poster poster discusses GPCR signaling pharmacology and highlights therapeutic applications of biased agonism.
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