5-HT1A Receptor Antagonists: Small Molecules and Peptides
5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.
7 results for "5-HT1A Receptor Antagonists Small Molecules and Peptides" in Products
7 results for "5-HT1A Receptor Antagonists Small Molecules and Peptides" in Products
5-HT1A Receptor Antagonists: Small Molecules and Peptides
5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.
Potent 5-HT1A antagonist; also D4 agonist
| Chemical Name: | N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate |
| Purity: | ≥99% (HPLC) |
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
| Chemical Name: | 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate |
| Purity: | ≥98% (HPLC) |
5-HT1A antagonist
| Chemical Name: | 1-(2-Methoxyphenyl)-4-(4-phthalimidobutyl)piperazine hydrobromide |
| Purity: | ≥98% (HPLC) |
Selective, high affinity 5-HT1A antagonist
| Chemical Name: | (3R)-3-(Dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective 5-HT1A antagonist
| Chemical Name: | (S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide dihydrochloride |
| Purity: | ≥99% (HPLC) |
β antagonist; also 5-HT1A antagonist
| Chemical Name: | 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent 5-HT1A partial agonist and SSRI; antidepressant
| Chemical Name: | 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide hydrochloride |
| Purity: | ≥98% |
