5-HT5 Receptor Antagonists: Small Molecules and Peptides
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. 5-HT5A belongs to the G protein-coupled receptor 1 family. 5-HT5A is also a member of the serotonin receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G proteins. 5-HT5A has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
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5-HT5 Receptor Antagonists: Small Molecules and Peptides
The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. 5-HT5A belongs to the G protein-coupled receptor 1 family. 5-HT5A is also a member of the serotonin receptor family. It is a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G proteins. 5-HT5A has been shown to function in part through the regulation of intracellular Ca2+ mobilization.
Selective 5-ht5a antagonist
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride |
| Purity: | ≥99% (HPLC) |
