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ACE-2: Proteins and Enzymes

Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.

ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. The binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.

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20 results for "ACE-2 Proteins and Enzymes" in Products

20 results for "ACE-2 Proteins and Enzymes" in Products

ACE-2: Proteins and Enzymes

Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.

ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. The binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.

Products:

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Analyzed by SEC-MALS

Applications: BA, EnzAct

Biotinylated via Amines

Applications: BA, EnzAct

Bioactive, High Spike RBD Binding

Applications: BA, EnzAct

Biotinylated

Applications: BA, EnzAct
Applications: BA, EnzAct
Applications: EnzAct
Applications: BA, EnzAct
Applications: BA, EnzAct

Biotinylated

Applications: BA
Applications: EnzAct
Applications: EnzAct

HEK293 Expressed

Applications: EnzAct
Applications: BA
Applications: EnzAct
Applications: AC
Applications: AC
Applications: AC
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