Additional Nitric Oxide Compounds: Small Molecules and Peptides
Nitric Oxide (NO) is a gaseous free radical with a short half-life in vivo of a few seconds or less. It is a pleiotropic biological mediator that regulates diverse activities ranging from neuronal function to immune system regulation. NO is catalyzed by enzymes of the Nitric Oxide Synthase (NOS) family, which include neuronal NOS (nNOS/NOS1), inducible NOS (iNOS/NOS2), and endothelial NOS (eNOS/NOS3). NO is lipid soluble, so it is not stored by synthesized de novo and freely diffuses across lipid membranes. NO mediates its effects on target cells via several different mechanisms. For instance, NO can activate Guanylyl Cyclase, which catalyzes the formation of the second messenger cGMP.
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Additional Nitric Oxide Compounds: Small Molecules and Peptides
Nitric Oxide (NO) is a gaseous free radical with a short half-life in vivo of a few seconds or less. It is a pleiotropic biological mediator that regulates diverse activities ranging from neuronal function to immune system regulation. NO is catalyzed by enzymes of the Nitric Oxide Synthase (NOS) family, which include neuronal NOS (nNOS/NOS1), inducible NOS (iNOS/NOS2), and endothelial NOS (eNOS/NOS3). NO is lipid soluble, so it is not stored by synthesized de novo and freely diffuses across lipid membranes. NO mediates its effects on target cells via several different mechanisms. For instance, NO can activate Guanylyl Cyclase, which catalyzes the formation of the second messenger cGMP.
GPR3 agonist; also inhibits NOS and NADPH oxidases
| Alternate Names: | DPI |
| Chemical Name: | [1,1'-Biphenyl]-2,2'-diyliodonium chloride |
| Purity: | ≥99% (HPLC) |
