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AKAP13 Products

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in at least 3 transcript variants encoding different isoforms containing a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway and, in addition, function as protein kinase A-anchoring proteins.
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33 results for "AKAP13" in Products

33 results for "AKAP13" in Products

AKAP13 Products

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in at least 3 transcript variants encoding different isoforms containing a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway and, in addition, function as protein kinase A-anchoring proteins.
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Applications: IHC, WB, ELISA
Reactivity: Human
Applications: IHC, ICC/IF
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Catalog #: H00011214-Q01
Applications: WB, ELISA, MA, AP, PAGE
Catalog #: H00011214-T02
Applications: WB
Applications: AC
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, Simple Western, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, Simple Western, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, Simple Western, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
Applications: IP, WB (-)
Reactivity: Human
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