Alkaline Ceramidase 2: Proteins and Enzymes

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Regulates the maturation ofintegrin beta-1 (ITGB1) by controlling the generation of sphingosine in the Golgi complex. Inhibits cell adhesion byreducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems todepend on the balance between sphingosine and sphingosine-1-phosphate