APC: Lysates
APC is a ubiquitous, tumor-suppressor protein. APC mutations are common in most colon cancers, generally resulting in a gene product that is truncated in the carboxy terminal region. APC contains several binding domains, including an EB1, DLG (PDZ sequence) and PSD-93 domain that bind to cytoskeletal elements. In addition to beta-catenin degradation, APC is involved in cell cycle, division and migration.
1 result for "APC Lysates" in Products
1 result for "APC Lysates" in Products
APC: Lysates
APC is a ubiquitous, tumor-suppressor protein. APC mutations are common in most colon cancers, generally resulting in a gene product that is truncated in the carboxy terminal region. APC contains several binding domains, including an EB1, DLG (PDZ sequence) and PSD-93 domain that bind to cytoskeletal elements. In addition to beta-catenin degradation, APC is involved in cell cycle, division and migration.
| Applications: | WB |
![Western Blot: APC Overexpression Lysate [NBP2-09451]](https://resources.bio-techne.com/images/products/APC-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09451-img0001.jpg "Western Blot: APC Overexpression Lysate [NBP2-09451]")