APP Products
Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.
Products:
12 results for "APP" in Products
12 results for "APP" in Products
APP Products
Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.
Products:
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC |
| Assay Range: | 0.625 - 20 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #304904 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat, Canine, Chicken, +1 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | P05067 |
| Applications: | InhibAct |
| Source: | E. coli |
| Applications: | WB |
Predominant amyloid β-protein fragment
| Purity: | ≥95% (HPLC) |
Amyloid β-protein fragment
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
Human amyloid β-protein fragment functionally required for neurotoxicity
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #128715 |
| Applications: | WB, IP |