Aurora Kinase Inhibitors: Small Molecules and Peptides
The mammalian Aurora kinase family contains three serine/threonine kinase members that participate in cell division. They impact cytokinesis and chromatid segregation during the G2/M phase of cell division. Aurora A influences centrosome maturation and spindle assembly, while Auroras B and C direct chromosome alignment and segregation.
4 results for "Aurora Kinase Inhibitors Small Molecules and Peptides" in Products
4 results for "Aurora Kinase Inhibitors Small Molecules and Peptides" in Products
Aurora Kinase Inhibitors: Small Molecules and Peptides
The mammalian Aurora kinase family contains three serine/threonine kinase members that participate in cell division. They impact cytokinesis and chromatid segregation during the G2/M phase of cell division. Aurora A influences centrosome maturation and spindle assembly, while Auroras B and C direct chromosome alignment and segregation.
Potent pan-Aurora kinase inhibitor
| Chemical Name: | N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine |
| Purity: | ≥98% (HPLC) |
Inhibits Aurora kinase B
| Chemical Name: | N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide |
| Purity: | ≥98% (HPLC) |
Potent Aurora kinase B inhibitor
| Chemical Name: | N-[2,3-Dihydro-2-oxo-3-[(3Z)-phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-1H-indol-5-yl]-ethanesulfonamide hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent, selective Aurora kinase A inhibitor
| Chemical Name: | 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride |
| Purity: | ≥98% (HPLC) |
