B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
61 results for "B7-1/CD80" in Products
61 results for "B7-1/CD80" in Products
B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready, ICC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![Flow Cytometry: B7-1/CD80 Antibody (16-10A1) - BSA Free [NBP1-43385]](https://resources.bio-techne.com/images/products/B7-1-CD80-Antibody-16-10A1-Flow-Cytometry-NBP1-43385-img0007.jpg "Flow Cytometry: B7-1/CD80 Antibody (16-10A1) - BSA Free [NBP1-43385]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: B7-1/CD80 Antibody [NBP2-48954]](https://resources.bio-techne.com/images/products/B7-1-CD80-Antibody-Immunohistochemistry-Paraffin-NBP2-48954-img0005.jpg "Immunohistochemistry-Paraffin: B7-1/CD80 Antibody [NBP2-48954]")
Recombinant Monoclonal Antibody
| Reactivity: | Cynomolgus Monkey |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Cynomolgus Monkey |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![B7-1/CD80 Antibody (16-10A1) [Alexa Fluor® 700]](https://resources.bio-techne.com/images/products/nbp1-43385af700_armenian-hamster-monoclonal-b7-1-cd80-antibody-16-10a1-alexa-fluor-700-317202398435.jpg "B7-1/CD80 Antibody (16-10A1) [Alexa Fluor® 700] [NBP1-43385AF700] -")
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![B7-1/CD80 Antibody (16-10A1) [Alexa Fluor® 488]](https://resources.bio-techne.com/images/products/nbp1-43385af488_armenian-hamster-monoclonal-b7-1-cd80-antibody-16-10a1-alexa-fluor-488-flow-cytometry-199202492658.png "Flow Cytometry: Armenian Hamster Monoclonal B7-1/CD80 Antibody (16-10A1) [Alexa Fluor® 488] [NBP1-43385AF488]")
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![B7-1/CD80 Antibody (16-10A1) [Alexa Fluor® 647]](https://resources.bio-techne.com/images/products/nbp1-43385af647_armenian-hamster-monoclonal-b7-1-cd80-antibody-16-10a1-alexa-fluor-647-24720231115347.jpg "B7-1/CD80 Antibody (16-10A1) [Alexa Fluor® 647] [NBP1-43385AF647] -")
Recombinant Monoclonal Antibody
| Reactivity: | Cynomolgus Monkey |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Cynomolgus Monkey |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Cynomolgus Monkey |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![B7-1/CD80 Antibody (16-10A1) [FITC]](https://resources.bio-techne.com/images/products/nbp1-43385f_armenian-hamster-monoclonal-b7-1-cd80-antibody-16-10a1-fitc-31720238133473.jpg "B7-1/CD80 Antibody (16-10A1) [FITC] [NBP1-43385F] -")
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Cynomolgus Monkey |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Cynomolgus Monkey |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![B7-1/CD80 Antibody (16-10A1) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nbp1-43385mfv610_armenian-hamster-b7-1-cd80-mab-16-10a1-mfv610-se-6720239172747.png "B7-1/CD80 Antibody (16-10A1) [mFluor Violet 610 SE] [NBP1-43385MFV610] -")
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![B7-1/CD80 Antibody (16-10A1) [Allophycocyanin]](https://resources.bio-techne.com/images/products/nbp1-43385apc_armenian-hamster-monoclonal-b7-1-cd80-antibody-16-10a1-allophycocyanin-31720239483917.jpg "B7-1/CD80 Antibody (16-10A1) [Allophycocyanin] [NBP1-43385APC] -")