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B7-1/CD80 Products

B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.

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526 results for "B7-1/CD80" in Products

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526 results for "B7-1/CD80" in Products

B7-1/CD80 Products

B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.

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Applications: Flow, IHC, CyTOF-ready, Dual ISH-IHC, Neut
Reactivity: Human
Applications: WB, Flow, CyTOF-ready, ICC, Neut
Reactivity: Mouse
Applications: WB, IHC
Reactivity: Human
Applications: IHC, WB, Flow
Reactivity: Human, Mouse
Applications: Flow
Reactivity: Human
Applications: IHC, WB, ICC/IF
Reactivity: Human
Applications: IHC
Reactivity: Mouse
Applications: Flow
Reactivity: Human
Applications: BA

(High Purity Dimer)

Applications: PAGE, Cell Depl
Applications: Flow
Reactivity: Human
Applications: BA

Fc Chimera

Applications: WB
Reactivity: Human
Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody.

Applications: IHC, Flow, IP
Reactivity: Human, Mouse, Feline
Applications: BA

Biotinylated

Applications: BA

Biotinylated

Applications: BA
Applications: WB
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Mouse

Recombinant Monoclonal Antibody.

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