B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
470 results for "B7-1/CD80" in Products
470 results for "B7-1/CD80" in Products
B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37711 |
| Applications: | Flow, IHC, CyTOF-ready, Dual ISH-IHC, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready, ICC, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #111114 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37711 |
| Applications: | Flow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #62N3G8 |
| Applications: | IHC, WB, Flow |
![Western Blot: B7-1/CD80 Antibody (62N3G8)BSA Free [NBP2-25255]](https://resources.bio-techne.com/images/products/B7-1-CD80-Antibody-62N3G8-Western-Blot-NBP2-25255-img0010.jpg "Western Blot: B7-1/CD80 Antibody (62N3G8)BSA Free [NBP2-25255]")
| Source: | NS0 |
| Accession #: | Q00609 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #OTI2E5 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: B7-1/CD80 Antibody (OTI2E5) [NBP2-02905]](https://resources.bio-techne.com/images/products/B7-1-CD80-Antibody-2E5-Western-Blot-NBP2-02905-img0019.jpg "Western Blot: B7-1/CD80 Antibody (OTI2E5) [NBP2-02905]")
| Source: | CHO |
| Accession #: | P33681 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37711 |
| Applications: | Flow |
| Source: | HEK293 |
| Accession #: | P33681 |
| Applications: | BA |
(High Purity Dimer)
| Source: | NS0 |
| Accession #: | P33681-1 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | P33681.1 |
| Applications: | BA |
| Applications: | PAGE, Cell Depl |
![SDS-PAGE: Recombinant Mouse B7-1/CD80 Protein [NBP2-26578]](https://resources.bio-techne.com/images/products/Recombinant-Mouse-B7-1-CD80-Protein-SDS-Page-NBP2-26578-img0002.jpg "SDS-PAGE: Recombinant Mouse B7-1/CD80 Protein [NBP2-26578]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37711 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #210408 |
| Applications: | WB |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
Fc Chimera
| Source: | CHO |
| Accession #: | P33681.1 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Kappa Monoclonal Clone #RM80 |
| Applications: | IHC, WB, ICC/IF, Flow, Func, +1 More |
![Immunocytochemistry/ Immunofluorescence: B7-1/CD80 Antibody (RM80) - Chimeric - Azide and BSA Free [NBP3-11976]](https://resources.bio-techne.com/images/products/B7-1-CD80-Antibody-RM80-Chimeric-Immunocytochemistry-Immunofluorescence-NBP3-11976-img0001.jpg "Immunocytochemistry/ Immunofluorescence: B7-1/CD80 Antibody (RM80) - Chimeric - Azide and BSA Free [NBP3-11976]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #37721 |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #2740B |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Feline |
| Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
| Applications: | IHC, Flow, IP |
![Flow Cytometry: B7-1/CD80 Antibody (16-10A1) - BSA Free [NBP1-43385]](https://resources.bio-techne.com/images/products/B7-1-CD80-Antibody-16-10A1-Flow-Cytometry-NBP1-43385-img0007.jpg "Flow Cytometry: B7-1/CD80 Antibody (16-10A1) - BSA Free [NBP1-43385]")
| Source: | HEK293 |
| Accession #: | P33681.1 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | P33681-1 |
| Applications: | BA |
