B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
526 results for "B7-1/CD80" in Products
526 results for "B7-1/CD80" in Products
B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #37711 |
Applications: | Flow, IHC, CyTOF-ready, Dual ISH-IHC, Neut |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, CyTOF-ready, ICC, Neut |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Human, Mouse |
Details: | Mouse IgG2b Kappa Monoclonal Clone #62N3G8 |
Applications: | IHC, WB, Flow |
Source: | NS0 |
Accession #: | Q00609 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #37711 |
Applications: | Flow |
Source: | CHO |
Accession #: | P33681 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #OTI2E5 |
Applications: | IHC, WB, ICC/IF |
Source: | HEK293 |
Accession #: | P33681 |
Applications: | BA |
Reactivity: | Mouse |
Details: | Rat IgG2a Monoclonal Clone #111114 |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #37711 |
Applications: | Flow |
(High Purity Dimer)
Source: | NS0 |
Accession #: | P33681-1 |
Applications: | BA |
Applications: | PAGE, Cell Depl |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #37711 |
Applications: | Flow |
Assay Range: | 62.5 - 4,000 pg/mL |
Applications: | ELISA |
Fc Chimera
Source: | CHO |
Accession #: | P33681.1 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #37721 |
Applications: | WB |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #2740B |
Applications: | Flow |
Reactivity: | Human, Mouse, Feline |
Details: | Armenian Hamster IgG Monoclonal Clone #16-10A1 |
Applications: | IHC, Flow, IP |
Biotinylated
Source: | CHO |
Accession #: | P33681.1 |
Applications: | BA |
Biotinylated
Source: | CHO |
Accession #: | P33681-1 |
Applications: | BA |
Source: | HEK293 |
Accession #: | P33681.1 |
Applications: | BA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #37711 |
Applications: | Flow |
Recombinant Monoclonal Antibody.
Reactivity: | Mouse |
Details: | Rabbit IgG Monoclonal Clone #2740B |
Applications: | Flow |