B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
33 results for "B7-1/CD80" in Products
33 results for "B7-1/CD80" in Products
B7-1/CD80 Products
B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20 - 100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C80/1608 |
| Applications: | ELISA |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
![B7-1/CD80 Antibody (2D10.4) [Allophycocyanin]](https://resources.bio-techne.com/images/products/nbp1-43384apc_mouse-monoclonal-b7-1-cd80-antibody-2d10-4-allophycocyanin-31720239534959.jpg "B7-1/CD80 Antibody (2D10.4) [Allophycocyanin] [NBP1-43384APC] -")
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, NULL |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
![B7-1/CD80 Antibody (2D10.4) [FITC]](https://resources.bio-techne.com/images/products/nbp1-43384f_mouse-monoclonal-b7-1-cd80-antibody-2d10-4-fitc-31720238124216.jpg "B7-1/CD80 Antibody (2D10.4) [FITC] [NBP1-43384F] -")
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
![B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 700]](https://resources.bio-techne.com/images/products/nbp1-43384af700_mouse-monoclonal-b7-1-cd80-antibody-2d10-4-alexa-fluor-700-3172023981674.jpg "B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 700] [NBP1-43384AF700] -")
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
![B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 647]](https://resources.bio-techne.com/images/products/nbp1-43384af647_mouse-monoclonal-b7-1-cd80-antibody-2d10-4-alexa-fluor-647-247202310585714.jpg "B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 647] [NBP1-43384AF647] -")
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
![B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 532]](https://resources.bio-techne.com/images/products/nbp1-43384af532_mouse-monoclonal-b7-1-cd80-antibody-2d10-4-alexa-fluor-532-31720238225215.jpg "B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 532] [NBP1-43384AF532] -")
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
Clone 2D10.4 was used by HLDA to establish CD designation.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2D10.4 |
| Applications: | Flow, Func |
![B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 350]](https://resources.bio-techne.com/images/products/nbp1-43384af350_mouse-monoclonal-b7-1-cd80-antibody-2d10-4-alexa-fluor-350-29820239311035.jpg "B7-1/CD80 Antibody (2D10.4) [Alexa Fluor® 350] [NBP1-43384AF350] -")