BACE-1: Lysates
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
1 result for "BACE-1 Lysates" in Products
1 result for "BACE-1 Lysates" in Products
BACE-1: Lysates
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
| Applications: | WB |
![Western Blot: BACE-1 Overexpression Lysate [NBP2-04325]](https://resources.bio-techne.com/images/products/BACE1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-04325-img0001.jpg "Western Blot: BACE-1 Overexpression Lysate [NBP2-04325]")