Bax-alpha Products
B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.
4 results for "Bax-alpha" in Products
4 results for "Bax-alpha" in Products
Bax-alpha Products
B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.
| Assay Range: | 312 - 20,000 pg/mL |
| Applications: | ELISA |
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines
| Chemical Name: | 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide |
| Purity: | ≥98% (HPLC) |
High affinity and selective activator of Bax
| Chemical Name: | 2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol |
| Purity: | ≥98% (HPLC) |
Allosteric inhibitor of Bax channel activation
| Alternate Names: | BAI1 |
| Chemical Name: | 3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanol dihydrochloride |
| Purity: | ≥98% (HPLC) |
