BMP-2/BMP-7 Heterodimer: Proteins and Enzymes
BMP-7, also known as osteogenic protein 1 (OP-1), and BMP-2 are TGF-beta superfamily cytokines that influence a variety of morphogenic processes, particularly during skeletal and renal development. BMP-2 and BMP-7 are co-expressed in some embryonic tissues and associate into a functional 38 kDa osteogenic dimer. In in vitro osteoblast differentiation assays and in vivo bone formation models, BMP-2/BMP-7 is significantly more potent than either homodimer.
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BMP-2/BMP-7 Heterodimer: Proteins and Enzymes
BMP-7, also known as osteogenic protein 1 (OP-1), and BMP-2 are TGF-beta superfamily cytokines that influence a variety of morphogenic processes, particularly during skeletal and renal development. BMP-2 and BMP-7 are co-expressed in some embryonic tissues and associate into a functional 38 kDa osteogenic dimer. In in vitro osteoblast differentiation assays and in vivo bone formation models, BMP-2/BMP-7 is significantly more potent than either homodimer.
| Source: | E. coli |
| Accession #: | NP_001191 (BMP-2) & NP_001710 (BMP-7) |
| Applications: | BA |
