CA125/MUC16 Products
The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.
162 results for "CA125/MUC16" in Products
162 results for "CA125/MUC16" in Products
CA125/MUC16 Products
The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.
| Source: | CHO |
| Accession #: | NP_078966.2 |
| Applications: | Bind |
| Sensitivity: | 0.099 U/mL |
| Applications: | ELISA |
| Assay Range: | 0.5 - 32 U/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine, Human Milk) |
For use with catalog number DCA125
| Applications: | Ctrl |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL2782 |
| Applications: | IHC, ICC/IF |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
