Caspase-10 Products
Caspase-10 (Cysteine-aspartic acid protease 10, FLICE2 and Mch4) is a 28-29 kDa member of the peptidase C14A family of enzymes. It is widely expressed in blood and epithelial cells. Caspase-10 appears to be an initiator caspase that acts on Pro-Caspases-3, -4, -6, -7, and -9. Cleavage of Pro-Caspase-1 generates a p43 subunit plus the small mature p12 subunit. Cleavage of p43 generates a prodomain p25 and a large mature p17 subunit. P17 and p12 noncovalently associate to form a 29 kDa mature heterodimer.
Products:
15 results for "Caspase-10" in Products
15 results for "Caspase-10" in Products
Caspase-10 Products
Caspase-10 (Cysteine-aspartic acid protease 10, FLICE2 and Mch4) is a 28-29 kDa member of the peptidase C14A family of enzymes. It is widely expressed in blood and epithelial cells. Caspase-10 appears to be an initiator caspase that acts on Pro-Caspases-3, -4, -6, -7, and -9. Cleavage of Pro-Caspase-1 generates a p43 subunit plus the small mature p12 subunit. Cleavage of p43 generates a prodomain p25 and a large mature p17 subunit. P17 and p12 noncovalently associate to form a 29 kDa mature heterodimer.
Products:
Promotes assembly and inhibits disassembly of microtubules
| Chemical Name: | [2aR-[2aα,4β,4aβ,6α,9α(αR*,βS*),11α,12α,12aα,12bα]]-β-(Benzoylamino)-α-hydroxy-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester benzenepropanoic acid |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #63131 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Source: | E. coli |
| Accession #: | AAC50644 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse, Rat, Canine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Immunohistochemistry-Paraffin: Caspase-10/FLICE2 Antibody [NB100-56125]](https://resources.bio-techne.com/images/products/Caspase-10-FLICE2-Antibody-Immunohistochemistry-Paraffin-NB100-56125-img0001.jpg "Immunohistochemistry-Paraffin: Caspase-10/FLICE2 Antibody [NB100-56125]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Caspase-10/FLICE2 Antibody [NBP1-87685]](https://resources.bio-techne.com/images/products/Caspase-10-FLICE2-Antibody-Western-Blot-NBP1-87685-img0004.jpg "Western Blot: Caspase-10/FLICE2 Antibody [NBP1-87685]")
| Applications: | AC |
| Applications: | ELISA |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #JE59-42 |
| Applications: | IHC, WB |
| Applications: | ELISA |
