CCL26/Eotaxin-3: ELISA Kits
CCL26, also known as Eotaxin-3 and SCYA26, is a small cytokine that is a member of the CC chemokine family. It is only 94 amino acids (aa) in length, with aa 1-23 serving as a putative signal peptide. Human CCL26/Eotaxin-3 has a predicted molecular weight of approximately 11 kDa, and the mature protein only shares 27% aa sequence identity with the mouse ortholog.
CCL26/Eotaxin-3 is constitutively expressed at low levels in various tissues including in the heart and ovary. Its expression is upregulated in vascular endothelial cells by IL-13 and IL-4. CCL26/Eotaxin-3 is a selective agonist for CCR3, as serves as a chemoattractant for cells that express CCR3, such as eosinophils, basophils, and Th2 cells. It has also been shown to act as an antagonist for the receptors CCR1 and CCR5. CCL26/Eotaxin-3 plays a role in allergic reactions.
Products:
4 results for "CCL26/Eotaxin-3 ELISA Kits" in Products
4 results for "CCL26/Eotaxin-3 ELISA Kits" in Products
CCL26/Eotaxin-3: ELISA Kits
CCL26, also known as Eotaxin-3 and SCYA26, is a small cytokine that is a member of the CC chemokine family. It is only 94 amino acids (aa) in length, with aa 1-23 serving as a putative signal peptide. Human CCL26/Eotaxin-3 has a predicted molecular weight of approximately 11 kDa, and the mature protein only shares 27% aa sequence identity with the mouse ortholog.
CCL26/Eotaxin-3 is constitutively expressed at low levels in various tissues including in the heart and ovary. Its expression is upregulated in vascular endothelial cells by IL-13 and IL-4. CCL26/Eotaxin-3 is a selective agonist for CCR3, as serves as a chemoattractant for cells that express CCR3, such as eosinophils, basophils, and Th2 cells. It has also been shown to act as an antagonist for the receptors CCR1 and CCR5. CCL26/Eotaxin-3 plays a role in allergic reactions.
Products:
| Sensitivity: | 0.215 pg/mL |
| Applications: | ELISA |
| Assay Range: | 3.13 - 200 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, Plasma) |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Applications: | ELISA, NULL |
![ELISA: Human CCL26/Eotaxin-3 ELISA Kit (Colorimetric) [KA2187]](https://resources.bio-techne.com/images/products/CCL26-Eotaxin-3-ELISA-Kit-[Biotin]-ELISA-KA2187-img0004.jpg "ELISA: Human CCL26/Eotaxin-3 ELISA Kit (Colorimetric) [KA2187]")
For use with catalog number DCC260B