CCL5/RANTES Products
CCL5/RANTES is a secreted beta-chemokine that plays a primary role in the inflammatory immune response through chemoattraction and activation of leukocytes that express CCR1, 3, 4, or 5. The two N-terminal residues of CCL5 can be removed by CD26/DPPIV, generating a protein that functions as a chemotaxis inhibitor. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells, and the vasculature. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1.
172 results for "CCL5/RANTES" in Products
172 results for "CCL5/RANTES" in Products
CCL5/RANTES Products
CCL5/RANTES is a secreted beta-chemokine that plays a primary role in the inflammatory immune response through chemoattraction and activation of leukocytes that express CCR1, 3, 4, or 5. The two N-terminal residues of CCL5 can be removed by CD26/DPPIV, generating a protein that functions as a chemotaxis inhibitor. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells, and the vasculature. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1.
| Sensitivity: | 6.6 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
| Sensitivity: | 2 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Citrate Plasma) |
Simple Plex CCL5/RANTES assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #21418 |
| Applications: | WB, Neut |
| Source: | E. coli |
| Accession #: | P13501 |
| Applications: | BA |
Simple Plex Mouse/Rat CCL5/RANTES assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #53405 |
| Applications: | ICC, Neut |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Primate |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | E. coli |
| Accession #: | Q5XZF2 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #21445 |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, Neut |
Control for use with Human and Non-Human Primate CCL5/RANTES Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #53433 |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Simple Plex Non-Human Primate RANTES assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #21445 |
| Applications: | ICFlow |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #16411 |
| Applications: | WB, Neut |
| Reactivity: | Feline |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Cotton Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
