CCL5/RANTES Products
CCL5/RANTES is a secreted beta-chemokine that plays a primary role in the inflammatory immune response through chemoattraction and activation of leukocytes that express CCR1, 3, 4, or 5. The two N-terminal residues of CCL5 can be removed by CD26/DPPIV, generating a protein that functions as a chemotaxis inhibitor. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells, and the vasculature. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1.
132 results for "CCL5/RANTES" in Products
132 results for "CCL5/RANTES" in Products
CCL5/RANTES Products
CCL5/RANTES is a secreted beta-chemokine that plays a primary role in the inflammatory immune response through chemoattraction and activation of leukocytes that express CCR1, 3, 4, or 5. The two N-terminal residues of CCL5 can be removed by CD26/DPPIV, generating a protein that functions as a chemotaxis inhibitor. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells, and the vasculature. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1.
| Sensitivity: | 6.6 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
| Sensitivity: | 2 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Citrate Plasma) |
| Source: | E. coli |
| Accession #: | P13501 |
| Applications: | BA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #21418 |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC, Neut |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Primate |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | E. coli |
| Accession #: | Q5XZF2 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #21445 |
| Applications: | WB, IHC, CyTOF-ready, ICFlow, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #53433 |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #21445 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Cotton Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Feline |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Cotton Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #21445 |
| Applications: | ICFlow |
| Reactivity: | Canine |
| Details: | Mouse IgG1 Monoclonal Clone #676106 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #21445 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #16411 |
| Applications: | WB, Neut |
| Source: | NS0 |
| Accession #: | P13501 (CCL5) & P78423 (CX3CL1 Mucin-like Stalk) |
| Applications: | BA |
| Reactivity: | Canine |
| Details: | Mouse IgG2b Monoclonal Clone #676117 |
| Applications: | Neut |
