CEACAM-1/CD66a: Proteins and Enzymes
CEACAM-1, also known as CD66a, is an immunoglobulin superfamily protein that is expressed on neutrophils, activated NK cells, bile duct and colonic epithelial cells, and endothelial cells. CEACAM-1 is heavily glycosylated and carries high mannose residues and (sialyl) Lewis-x. It is expressed as at least three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic regions. It engages in homotypic adhesion and heterotypic adhesion with CEACAM-3/CD66d and CEACAM-6/CD66c. On neutrophils, CEACAM-1 additionally binds to dendritic cell DC-SIGN via its Lewis-x moiety, inducing dendritic cell maturation and a subsequent Th1-type response.
Products:
4 results for "CEACAM-1/CD66a Proteins and Enzymes" in Products
4 results for "CEACAM-1/CD66a Proteins and Enzymes" in Products
CEACAM-1/CD66a: Proteins and Enzymes
CEACAM-1, also known as CD66a, is an immunoglobulin superfamily protein that is expressed on neutrophils, activated NK cells, bile duct and colonic epithelial cells, and endothelial cells. CEACAM-1 is heavily glycosylated and carries high mannose residues and (sialyl) Lewis-x. It is expressed as at least three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic regions. It engages in homotypic adhesion and heterotypic adhesion with CEACAM-3/CD66d and CEACAM-6/CD66c. On neutrophils, CEACAM-1 additionally binds to dendritic cell DC-SIGN via its Lewis-x moiety, inducing dendritic cell maturation and a subsequent Th1-type response.
Products:
| Applications: | AC |
Biotinylated Avi-tag
| Source: | HEK293 |
| Accession #: | P13688.2 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P13688 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | P13688.2 |
| Applications: | BA |
