Chitinase 3-like 1/YKL-40 Products
Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.
CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.
Products:
73 results for "Chitinase 3-like 1/YKL-40" in Products
73 results for "Chitinase 3-like 1/YKL-40" in Products
Chitinase 3-like 1/YKL-40 Products
Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.
CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.
Products:
| Sensitivity: | 8.15 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC |
| Source: | NS0 |
| Accession #: | P36222 |
| Applications: | BA |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Primate |
| Details: | Rat IgG1 Monoclonal Clone #384327 |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human, Primate |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL12241 |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: Chitinase 3-like 1 Antibody [NBP3-21212] -](https://resources.bio-techne.com/images/products/nbp3-21212_mouse-chitinase-3-like-1-mab-cl12241-45202315534325.jpg "Immunohistochemistry-Paraffin: Chitinase 3-like 1 Antibody [NBP3-21212] -")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL12314 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #7T1R3 |
| Applications: | WB, ICC/IF |
![Western Blot: Chitinase 3-like 1/YKL-40 Antibody (7T1R3) [NBP3-16077]](https://resources.bio-techne.com/images/products/Chitinase-3-like-1-Antibody-9P1P6-Western-Blot-NBP3-16077-img0003.jpg "Western Blot: Chitinase 3-like 1/YKL-40 Antibody (7T1R3) [NBP3-16077]")
| Reactivity: | Human, Monkey, Virus |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]](https://resources.bio-techne.com/images/products/Chitinase-3-like-1-Antibody-Western-Blot-NBP1-57913-img0001.jpg "Western Blot: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
| Applications: | WB |
![Western Blot: Chitinase 3-like 1/YKL-40 Overexpression Lysate [NBP2-08222]](https://resources.bio-techne.com/images/products/CHI3L1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-08222-img0001.jpg "Western Blot: Chitinase 3-like 1/YKL-40 Overexpression Lysate [NBP2-08222]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/Immunofluorescence: Chitinase 3-like 1 Antibody [NBP3-21409] -](https://resources.bio-techne.com/images/products/nbp3-21409_rabbit-chitinase-3-like-1-pab-45202315493281.jpg "Immunocytochemistry/Immunofluorescence: Chitinase 3-like 1 Antibody [NBP3-21409] -")
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #C4 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
For use with catalog number DC3L10
| Applications: | Ctrl |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |