Chordin-like 2/CHRDL2 Products
Chordin-like 2 (CHL2, CHRDL2, or BNF-1), is a secreted glycoprotein that functions as a BMP antagonist. It is expressed in chondrocytes in developing joint cartilage, osteoblasts, myotubes, brain, some carcinomas, and the genitourinary system (e.g. uterus, prostate, testis, bladder).
CHL2 binds to multiple TGF-beta superfamily proteins including BMP-2, -4, -5, -6, -7, GDF-5, Activin A, and TSG. It prevents the binding of BMPs to type 1 and type 2 receptors as well as BMP-induced cellular responses. CHL2 reduces the rate of matrix deposition by mesenchymal cells, acting as a negative regulator of cartilage formation.
Products:
54 results for "Chordin-like 2/CHRDL2" in Products
54 results for "Chordin-like 2/CHRDL2" in Products
Chordin-like 2/CHRDL2 Products
Chordin-like 2 (CHL2, CHRDL2, or BNF-1), is a secreted glycoprotein that functions as a BMP antagonist. It is expressed in chondrocytes in developing joint cartilage, osteoblasts, myotubes, brain, some carcinomas, and the genitourinary system (e.g. uterus, prostate, testis, bladder).
CHL2 binds to multiple TGF-beta superfamily proteins including BMP-2, -4, -5, -6, -7, GDF-5, Activin A, and TSG. It prevents the binding of BMPs to type 1 and type 2 receptors as well as BMP-induced cellular responses. CHL2 reduces the rate of matrix deposition by mesenchymal cells, acting as a negative regulator of cartilage formation.
Products:
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #328905 |
| Applications: | WB, IHC, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | WB, CyTOF-ready, ICFlow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #272919 |
| Applications: | WB, IP |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Chordin-like 2/CHRDL2 Antibody [NBP1-88560]](https://resources.bio-techne.com/images/products/CHRDL2-Antibody-Western-Blot-NBP1-88560-img0005.jpg "Western Blot: Chordin-like 2/CHRDL2 Antibody [NBP1-88560]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/Immunofluorescence: Chordin-like 2/CHRDL2 Antibody [NBP3-21403] -](https://resources.bio-techne.com/images/products/nbp3-21403_rabbit-chordin-like-2-chrdl2-pab-45202315502321.jpg "Immunocytochemistry/Immunofluorescence: Chordin-like 2/CHRDL2 Antibody [NBP3-21403] -")
| Applications: | ELISA |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #272905 |
| Applications: | WB, Flow, CyTOF-ready |