CRMB: Proteins and Enzymes
CRMB is one of several cytokine response modifiers encoded by poxviruses such as variola (the causative agent of human smallpox). It has an N-terminal domain that binds TNF and lymphotoxin alpha and a C-terminal domain that binds several chemokines. CRM proteins shield poxviruses from proinflammatory and antiviral immune responses.
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CRMB: Proteins and Enzymes
CRMB is one of several cytokine response modifiers encoded by poxviruses such as variola (the causative agent of human smallpox). It has an N-terminal domain that binds TNF and lymphotoxin alpha and a C-terminal domain that binds several chemokines. CRM proteins shield poxviruses from proinflammatory and antiviral immune responses.
Source: | NS0 |
Accession #: | P34015 |
Applications: | BA |