CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
484 results for "CTLA-4" in Products
484 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Antitope patent anti-CTLA4 |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Antitope patent anti-CTLA4 |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Antitope patent anti-CTLA4 |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6864R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Antitope patent anti-CTLA4 |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
Applications: | IHC |
Source: | CHO |
Accession #: | P16410 |
Applications: | BA |
Source: | Sf 21 (baculovirus) |
Accession #: | Q6GR94 |
Applications: | BA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, CyTOF-ready, ICC |
Source: | NS0 |
Accession #: | Q6GTR6 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
Applications: | IHC, ICC/IF, ELISA, Flow, IP |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #48815 |
Applications: | WB |
Assay Range: | 125 - 8,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | Flow |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Rat IgG2a Monoclonal Clone #63828 |
Applications: | Flow |
Reactivity: | Mouse |
Details: | Rat IgG2a Monoclonal Clone #63828 |
Applications: | Flow |