CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
484 results for "CTLA-4" in Products
484 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Kappa Monoclonal Clone #9H10 |
| Applications: | WB, ELISA, Flow, B/N |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Kappa Monoclonal Clone #9H10 |
| Applications: | WB, ELISA, Flow, B/N |
| Reactivity: | Human, Mouse, Rat, Bovine |
| Details: | Mouse IgG1 kappa Monoclonal Clone #L4P2F5*F10 |
| Applications: | IHC, WB, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #tremelimumab |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0199-6G10 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Kappa Monoclonal Clone #9H10 |
| Applications: | WB, ELISA, Flow, B/N |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0199-6G10 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, ELISA, ICC/IF, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ipilimumab |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Kappa Monoclonal Clone #9H10 |
| Applications: | WB, ELISA, Flow, B/N |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #tremelimumab |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #quavonlimab |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ipilimumab |
| Applications: | ELISA, Flow, Func |