DAP12 Products
DAP12, also known as TYROBP and KARAP, is a transmembrane protein that functions as a signal transduction adaptor molecule. DAP12 is expressed as a disulfide-linked homodimer that associates with a variety of receptors on NK and myeloid cells. Complex formation is mediated by intramembrane ionic interaction between an aspartic acid residue in DAP12 and a lysine residue in the partnered receptor. Ligation of these receptors can trigger either cell activation or inhibition through the ITAM sequence in DAP12, resulting in activation of Src family tyrosine kinases. Human and mouse DAP12 share 73% amino acid sequence identity.
35 results for "DAP12" in Products
35 results for "DAP12" in Products
DAP12 Products
DAP12, also known as TYROBP and KARAP, is a transmembrane protein that functions as a signal transduction adaptor molecule. DAP12 is expressed as a disulfide-linked homodimer that associates with a variety of receptors on NK and myeloid cells. Complex formation is mediated by intramembrane ionic interaction between an aspartic acid residue in DAP12 and a lysine residue in the partnered receptor. Ligation of these receptors can trigger either cell activation or inhibition through the ITAM sequence in DAP12, resulting in activation of Src family tyrosine kinases. Human and mouse DAP12 share 73% amino acid sequence identity.
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: DAP12 Antibody [NBP1-85313]](https://resources.bio-techne.com/images/products/DAP12-Antibody-Immunohistochemistry-Paraffin-NBP1-85313-img0010.jpg "Immunohistochemistry-Paraffin: DAP12 Antibody [NBP1-85313]")
| Details: | Mouse IgG2a Monoclonal Clone #406209 |
| Applications: | Flow |
| Reactivity: | Human, Canine, Monkey, Primate, Equine, +1 More |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, ELISA, Flow |
![Immunohistochemistry-Paraffin: DAP12 Antibody [NBP1-52376]](https://resources.bio-techne.com/images/products/DAP12-Antibody-Immunohistochemistry-Paraffin-NBP1-52376-img0002.jpg "Immunohistochemistry-Paraffin: DAP12 Antibody [NBP1-52376]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR3887 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Applications: | WB, ELISA, MA, AP |
| Applications: | WB, ELISA, MA, AP |
| Applications: | AC |
| Applications: | WB |
![Western Blot: DAP12 Overexpression Lysate [NBL1-17484]](https://resources.bio-techne.com/images/products/DAP12-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-17484-img0002.jpg "Western Blot: DAP12 Overexpression Lysate [NBL1-17484]")
| Applications: | WB |
![Western Blot: DAP12 Overexpression Lysate [NBL1-17483]](https://resources.bio-techne.com/images/products/DAP12-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-17483-img0002.jpg "Western Blot: DAP12 Overexpression Lysate [NBL1-17483]")
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | NULL |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | NULL |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | NULL |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | NULL |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |
| Details: | Mouse IgG2A Monoclonal Clone #406209 |
| Applications: | Flow |