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Dkk-1 Products

Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.

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5 results for "Dkk-1" in Products

5 results for "Dkk-1" in Products

Dkk-1 Products

Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.

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Applications: WB, Block, KO
Reactivity: Human, Mouse
Applications: WB, IHC
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Rat
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