Dkk-1 Products
Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.
159 results for "Dkk-1" in Products
159 results for "Dkk-1" in Products
Dkk-1 Products
Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling. It interacts with LRP-6, and internalized complexes of Dkk-1/LRP-6/Kremen 2 can downregulate Wnt signaling. The balance between Wnt signaling and Dkk-1 inhibition is critical for bone formation and homeostasis. In addition, Dkk-1 can act as either a tumor suppressor or promoter of metastasis.
| Source: | Sf 21 (baculovirus) |
| Accession #: | O94907 |
| Applications: | BA |
| Sensitivity: | 0.948 pg/mL |
| Applications: | ELISA |
| Assay Range: | 9.38 - 600 pg/mL (Cell Culture Supernates, Serum-free Cell Culture Supern, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma) |
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
| Source: | CHO |
| Accession #: | O54908 |
| Applications: | BA |
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Simple Plex Human DKK-1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
| Sensitivity: | 29.6 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Block, KO |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Yeast |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2A5 |
| Applications: | IHC, WB, ICC/IF, ELISA, IP, +1 More |
![Western Blot: Dkk-1 Antibody (2A5) [H00022943-M11]](https://resources.bio-techne.com/images/products/Dkk-1-Antibody-2A5-Western-Blot-H00022943-M11-img0012.jpg "Western Blot: Dkk-1 Antibody (2A5) [H00022943-M11]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #141135 |
| Applications: | IHC |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #259631 |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | CHO |
| Accession #: | O94907.1 |
| Applications: | BA |
| Assay Range: | 46.9 - 3,000 pg/mL |
| Applications: | ELISA |
| Source: | CHO |
| Accession #: | XP_005565907.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | NP_001099820 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #141119 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #259631 |
| Applications: | WB, IHC |
Control for use with Human Dkk-1 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Source: | Sf 21 (baculovirus) |
| Accession #: | O94907 |
| Applications: | BA |
