Dopamine D2 Receptor Antagonists: Small Molecules and Peptides
DRD2 encodes the D2 subtype of the dopamine receptor that inhibits adenylyl cyclase activity. Alternative splicing of this G protein-coupled receptor results in two transcript variants encoding different isoforms. DRD2 plays a major role in the neural circuitry that mediates behavioral control, an ability that is essential for adaptive responding and is compromised in a variety of common neuropsychiatric disorders.
5 results for "Dopamine D2 Receptor Antagonists Small Molecules and Peptides" in Products
5 results for "Dopamine D2 Receptor Antagonists Small Molecules and Peptides" in Products
Dopamine D2 Receptor Antagonists: Small Molecules and Peptides
DRD2 encodes the D2 subtype of the dopamine receptor that inhibits adenylyl cyclase activity. Alternative splicing of this G protein-coupled receptor results in two transcript variants encoding different isoforms. DRD2 plays a major role in the neural circuitry that mediates behavioral control, an ability that is essential for adaptive responding and is compromised in a variety of common neuropsychiatric disorders.
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
| Alternate Names: | ICI 204,636 |
| Chemical Name: | 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate |
| Purity: | ≥99% (HPLC) |
High affinity D2 antagonist
| Chemical Name: | 3-[[4-(4-Chlorophenyl)-4-hydroxypiperidin-l-yl]methyl-1H-indole |
| Purity: | ≥98% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
| Chemical Name: | 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine |
| Purity: | ≥99% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
| Alternate Names: | R 64 766 |
| Chemical Name: | 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥99% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
| Alternate Names: | 9-Hydroxyrisperidone,9-OH-risperidone |
| Chemical Name: | 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
