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E-Cadherin: Simple Plex

E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

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3 results for "E-Cadherin Simple Plex" in Products

3 results for "E-Cadherin Simple Plex" in Products

E-Cadherin: Simple Plex

E-Cadherin/Cadherin-1 (ECAD) Is a transmembrane cell adhesion protein. It forms homophilic clusters between epithelial cells and is a critical component of adherens junctions. These junctions are critical for the maintenance of the epithelial barrier and epithelial tissue homeostasis. Decreased E-Cadherin is associated with physiological and pathological epithelial-to-mesenchymal transition (EMT) and cell migration, and E-Cadherin loss contributes to cancer metastasis. The shed ECD is released as a soluble factor that enhances cancer cell motility and EGFR-dependent survival and proliferation.

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Applications: Simple Plex
Applications: Simple Plex

Simple Plex Human E-Cadherin assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: Ctrl, Simple Plex

Control for use with Human E-Cadherin Simple Plex Cartridge Kit

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